Drug allergies are often reported but are uncommonly confirmed with diagnostic testing. At Allergy and Asthma Specialists of Greater Washington, we offer drug skin testing and oral challenges to determine whether a patient can safely take a specific medication. Our leading allergists in Chantilly, Gainesville, Warrenton, Culpeper, and Front Royal, Virginia perform these tests in a safe, controlled environment. Schedule your appointment by calling the most convenient clinic location or requesting an appointment online.

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What is drug allergy testing and how is it performed?

Drug allergy testing is used to determine whether a patient is truly allergic to a medication, such as penicillin. ​Testing typically begins with a skin test, where a small amount of the suspected drug is placed on the skin. If more sensitive evaluation is needed, intradermal testing may be performed, in which a tiny amount of penicillin is injected just under the skin’s surface. The area is monitored for redness, swelling, or a raised bump, which may indicate an allergic reaction.

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Why and who should consider drug allergy testing?

Many patients who believe they are allergic to a medication are not truly allergic. Drug allergy testing can safely determine whether a medication can be used, helping avoid unnecessary avoidance of important treatments and ensuring proper care. Testing is especially helpful for patients with a history of a possible drug allergy, whether from childhood or adulthood, who want to clarify their allergy status.

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What is a drug challenge?

A drug challenge is a medical test used to determine whether a patient can safely take a medication after allergy testing. During the challenge, the patient is given gradually increasing doses of the drug in a controlled, monitored setting. Allergists watch closely for any signs of an allergic reaction, such as hives, swelling, or breathing difficulties.

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Drug challenges are often performed after negative skin or intradermal tests to confirm that the medication is safe to use. This approach helps avoid unnecessary avoidance of important medications and ensures patients receive the most effective treatment.